Sulfamic Acid → 2-Methoxy-5-methylsulfanilic acid
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:7]([CH3:10])=[CH:8][CH:9]=1)[NH2:6].[S:11](=[O:15])(=[O:14])([OH:13])N>C(#N)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:6])[C:7]([CH3:10])=[CH:8][C:9]=1[S:11]([OH:15])(=[O:14])=[O:13]参加物
4
実験手順
23.1 g of 3-methoxy-6-methylaniline and 16.4 g of sulfamic acid were put into a 100 ml egg-plant type flask and the mixture was heated to temperature of from 150° to 160° C. and maintained thereat for 2 hours. Acetonitrile was added to the reaction mixture and the crystals thus deposited were collected. The crystals were dissolved in an aqueous solution of sodium hydroxide, the solution was filtered and acidified with hydrochloric acid, and the crystals thus deposited were collected by filtration.
後処理
- temperaturethe mixture was heated to temperature of from 150° to 160° C.
- temperaturemaintained
- customthe crystals thus deposited were collected
- dissolutionThe crystals were dissolved in an aqueous solution of sodium hydroxide
- filtrationthe solution was filtered
- filtrationthe crystals thus deposited were collected by filtration
出典と根拠
- ORDレコード
- ord-10a5e567c3634c778989865c564fb6c3
- 出典データセット
- uspto-grants-1988_02
- 特許番号
- US04725531
反応ノート
読み込み中…