Fenteracol → 2-(2,4,5-Trichloro-phenoxy)-ethyl 2-[4-(4-chlorophenoxymethyl)-phenoxy]-propionate

HRID 426438

反応式

HRID 426438 の反応式
[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([O:6][CH2:7][C:8]2[CH:20]=[CH:19][C:11]([O:12][CH:13]([CH3:18])[C:14]([O:16][CH3:17])=[O:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[Cl:23][C:24]1[CH:33]=[C:32]([Cl:34])[C:31]([Cl:35])=[CH:30][C:25]=1[O:26][CH2:27]CO.[Na]>CC(C)=O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][CH2:7][C:8]2[CH:20]=[CH:19][C:11]([O:12][CH:13]([CH3:18])[C:14]([O:16][CH2:17][CH2:27][O:26][C:25]3[CH:30]=[C:31]([Cl:35])[C:32]([Cl:34])=[CH:33][C:24]=3[Cl:23])=[O:15])=[CH:10][CH:9]=2)=[CH:21][CH:22]=1

参加物

5

反応物 3

HCID 16462FenteracolHCID 5360545SodiumHCID 19834514Methyl 2-[4-(4-Chlorophenoxy-methyl)-phenoxy]-propionate

生成物 1

HCID 538539382-(2,4,5-Trichloro-phenoxy)-ethyl 2-[4-(4-chlorophenoxymethyl)-phenoxy]-propionate

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A mixture consisting of 2.2 gm of methyl 2-[4-(4-chlorophenoxy-methyl)-phenoxy]-propionate, 2.4 gm of 2-(2,4,5-trichloro-phenoxy)-ethanol and 0.03 gm of sodium was heated at about 120°-150° C. and a pressure of 150 mm Hg for four hours. After cooling, the reaction mixture was briefly boiled with acetone, the cooled solution was filtered, and the solvent was removed from the filtrate in vacuo. The residue was recrystallized from ethanol/water, yielding 1.3 gm (36% of theory) of the compound of the formula ##STR19## which had a melting point of 83° C.

後処理

  1. temperaturewas heated at about 120°-150° C.
  2. temperatureAfter cooling
  3. filtrationthe cooled solution was filtered
  4. customthe solvent was removed from the filtrate in vacuo
  5. customThe residue was recrystallized from ethanol/water
  6. customyielding 1.3 gm (36% of theory) of the compound of the formula ##STR19## which

出典と根拠

ORDレコード
ord-fac85202ceaa4c29acd8b6831978d813
出典データセット
uspto-grants-1979_10
特許番号
US04169720

関連ノート

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