Benzoic Acid → 1-Phenyl-1-propanone

HRID 426902

反応式

HRID 426902 の反応式
C(O)(=O)CC.C(O)(=O)C1C=CC=CC=1.O.[C:16]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:20])[CH:17](C)[CH3:18]>>[C:16]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:20])[CH2:17][CH3:18]

参加物

5

反応物 4

HCID 243Benzoic Acid2 回HCID 962WaterHCID 1032Propionic AcidHCID 69144Isobutyrophenone

生成物 1

HCID 71481-Phenyl-1-propanone収率 2,360.1%

実験手順

In Example 1, using the reactor described above, together with ancillary equipment, a mixture containing 2 moles of propionic acid per mole of benzoic acid was fed to the reactor together with 4 moles of water per mole of benzoic acid at a rate of 249 ml/hr. for 4.5 hours. The reaction temperature was maintained between 445° C. and 450° C. Analysis of the condensed organic layer by gas chromatography indicated that 4.68 pounds of isobutyrophenone were produced per 100 pounds of propiophenone. These data are delineated in Table I. The instrument used was a Bendix Model 2300 dual column programmed temperature gas chromatograph having a thermal conductivity detector. The bridge current was 200 ma. with a 0-1 mv. recorder. The column consisted of two, 10 feet by 1/8 inch stainless steel tubing packed with silicone on an inert support. The column temperature was 190° C. The carrier gas was helium at 30 cc/minute.

後処理

  1. temperatureThe reaction temperature was maintained between 445° C. and 450° C

出典と根拠

ORDレコード
ord-063298aeb3d64e87a52b5597fe35919b
出典データセット
uspto-grants-1979_10
特許番号
US04172097

関連ノート

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