Pentanoyl chloride, 4-methyl- → 2-(4-Methyl-1-oxopentyl)furan

HRID 427225ノート

反応式

HRID 427225 の反応式
C([Sn](CCCC)(CCCC)[C:6]1[O:7][CH:8]=[CH:9][CH:10]=1)CCC.[CH3:19][CH:20]([CH3:26])[CH2:21][CH2:22][C:23](Cl)=[O:24]>C1COCC1.Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>[CH3:19][CH:20]([CH3:26])[CH2:21][CH2:22][C:23]([C:6]1[O:7][CH:8]=[CH:9][CH:10]=1)=[O:24]

参加物

5

反応物 2

HCID 170008Pentanoyl chloride, 4-methyl-HCID 43936882-(Tributylstannyl)furan

生成物 1

HCID 952872-(4-Methyl-1-oxopentyl)furan

試薬・触媒・溶媒 2

HCID 178418476HCID 178418476、化合物触媒HCID 8028Tetrahydrofuran溶媒

実験手順

A solution of 2-tributylstannylfuran (1 mmol), 4-methylvaleroyl chloride (1.1 mmol), and PdCl2(PPh3)2 (0.05 mmol) in THF was stirred at 25° C. for 24 h. Extraction and chromatography gave 2-(4-methylvaleryl)furan.

後処理

  1. extractionExtraction and chromatography

出典と根拠

ORDレコード
ord-4b7281dd45df4ecebc4c09ab97e8a6b1
出典データセット
uspto-grants-2001_11
特許番号
US06312662B1

反応ノート

読み込み中…