Sodium borohydride → (2-Isopropyl-6-methylphenyl)methanol
反応式
[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH:6]=[O:7])([CH3:3])[CH3:2].[BH4-].[Na+]>CO>[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH2:6][OH:7])([CH3:3])[CH3:2]参加物
4
実験手順
To a solution of 2-isopropyl-6-methylbenzaldehyd (1.75 g, 10.8 mmol) in methanol (15 ml) was added sodium borohydride (0.35 g, 9.5 mmol) and the mixture was stirred 1 h. at room temperature. The solvent was evaporated under reduced pressure and to the residue was added hexane and water. The organic layer was separated and evaporated under reduced pressure to give 1.73 g (98%) of the title compound as an oil.
後処理
- customThe solvent was evaporated under reduced pressure and to the residue
- additionwas added hexane and water
- customThe organic layer was separated
- customevaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-e446b94faa7448ce83e2e8534874030c
- 出典データセット
- uspto-grants-2001_11
- 特許番号
- US06313137B1
反応ノート
読み込み中…