Thionyl Chloride → 3-(Tribromomethanesulfonyl)benzoyl chloride

HRID 429599ノート

反応式

HRID 429599 の反応式
[Br:1][C:2]([Br:16])([Br:15])[S:3]([C:6]1[CH:7]=[C:8]([CH:12]=[CH:13][CH:14]=1)[C:9](O)=[O:10])(=[O:5])=[O:4].S(Cl)([Cl:19])=O>CN(C)C=O>[Br:1][C:2]([Br:16])([Br:15])[S:3]([C:6]1[CH:7]=[C:8]([CH:12]=[CH:13][CH:14]=1)[C:9]([Cl:19])=[O:10])(=[O:5])=[O:4]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 224660403-(Tribromomethanesulfonyl)benzoic acid

生成物 1

HCID 224660413-(Tribromomethanesulfonyl)benzoyl chloride

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

To 3-tribromomethanesulfonylbenzoic acid (B) obtained in the above-described (Step 1) are added dimethylformamide and thionyl chloride and the mixture is refluxed for one hour. The reaction mixture is filtered, and hexane is added to the filtrate to deposit crystals. The crystals are recovered by filtration and dried to obtain 3-tribromomethanesulfonyl benzoylchloride (C) as white crystals.

後処理

  1. temperaturethe mixture is refluxed for one hour
  2. filtrationThe reaction mixture is filtered
  3. additionhexane is added to the filtrate to deposit crystals
  4. filtrationThe crystals are recovered by filtration
  5. customdried

出典と根拠

ORDレコード
ord-36ed2f9674c14e5ab5417fa3dbeec0b7
出典データセット
uspto-grants-2001_11
特許番号
US06316670B1

反応ノート

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