化工社化工社 化学情報印刷レポート · 研究参考用
1-Ethynyl-4-fluorobenzene → Z-4-fluorostyryl 2-chlorobenzylsulfide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Ethynyl-4-fluorobenzene | HCID 522627 | — |
| 反応物 | 2-Chlorobenzyl mercaptan | HCID 580759 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 生成物 | Z-4-fluorostyryl 2-chlorobenzylsulfide | HCID 86588942 | — |
反応手順
A solution of 4-fluorophenylacetylene (0.02 mol) and 2-chlorobenzyl mercaptan (0.02 mol) and metallic sodium (0.02 g atom) was subjected to Procedure 2 to form (Z)-4-fluorostyryl 2-chlorobenzylsulfide. The title compound was obtained in 74% yield following oxidation. 1HNMR (CDC13) δ4.55 (2H, s), 6.66 (1H, d, JH,H=11.94), 7.20-7.65 (8H aromatic+1H ethylenic).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06656973B2 |
| 出典データセット | uspto-grants-2003_12 |
| ORD ID | ord-d57330e792bf444080d3a26cba83ac7b |
| 出典メモ | uspto-grants-2003_12 |