3-Phenoxybenzoic acid → 3-Phenoxybenzoyl chloride

HRID 431892

反応式

HRID 431892 の反応式
[O:1]([C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11](O)=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(Cl)(=O)C([Cl:20])=O>CN(C)C=O>[O:1]([C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([Cl:20])=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 195393-Phenoxybenzoic acidHCID 65578Oxalyl chloride

生成物 1

HCID 27603413-Phenoxybenzoyl chloride

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

3-Phenoxybenzoic acid (214 mg, 1.0 mmol) was treated with a solution of oxalyl chloride (1.5 mL of 2 M in dichloromethane, 3 mmol) and a catalytic amount of N,N-dimethylformamide. The reaction was stirred overnight at ambient temperature. The excess oxalyl chloride was removed in vacuo to afford 3-phenoxybenzoyl chloride.

後処理

  1. customThe excess oxalyl chloride was removed in vacuo

出典と根拠

ORDレコード
ord-e763b04a7795469197e5ffe53186d938
出典データセット
uspto-grants-2003_12
特許番号
US06660753B2

関連ノート

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