反応式
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([F:12])[C:10]=1[F:11])[C:5](O)=[O:6].C(Cl)(=O)C([Cl:16])=O.CN(C)C=O>ClCCl>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([F:12])[C:10]=1[F:11])[C:5]([Cl:16])=[O:6]参加物
5
実験手順
3,4,5-Trifluorobenzoic acid (0.176 g, 1.0 mmol) in dichloromethane (1.5 mL) was treated with a solution of oxalyl chloride (1.5 mL of 2 M in dichloromethane, 3 mmol) and a catalytic amount of N,N-dimethylformamide. The reaction was stirred overnight at ambient temperature. The excess oxalyl chloride was removed in vacuo to afford 3,4,5-trifluorobenzoyl chloride.
後処理
- customThe excess oxalyl chloride was removed in vacuo
出典と根拠
- ORDレコード
- ord-4b5b0fa67ece481b83ddb595cf6bd416
- 出典データセット
- uspto-grants-2003_12
- 特許番号
- US06660753B2
関連ノート
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