Methyl 2-(3-formylphenoxy)propanoate → Methyl 2-(3-hydroxymethylphenoxy)propionate
反応式
[CH:1]([C:3]1[CH:4]=[C:5]([CH:13]=[CH:14][CH:15]=1)[O:6][CH:7]([CH3:12])[C:8]([O:10][CH3:11])=[O:9])=[O:2].[H][H]>[Pd].C(OCC)(=O)C>[OH:2][CH2:1][C:3]1[CH:4]=[C:5]([CH:13]=[CH:14][CH:15]=1)[O:6][CH:7]([CH3:12])[C:8]([O:10][CH3:11])=[O:9]参加物
5
実験手順
Into 100 ml of ethyl acetate was dissolved 5.09 g of methyl 2-(3-formylphenoxy)propionate; 0.57 g of 10% palladium on carbon was added; the mixture was stirred for 30 minutes in a hydrogen atmosphere at atmospheric pressure. The reaction solution was filtered; the filtrate was concentrated and the residue was subjected to silica gel column chromatography to give 3.20 g of methyl 2-[3-(hydroxymethyl)phenoxy]propionate.
後処理
- filtrationThe reaction solution was filtered
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-58b38a03e761408798277ae8a9aacb14
- 出典データセット
- uspto-grants-2003_12
- 特許番号
- US06664214B1
反応ノート
読み込み中…