Ethyl 2-pyridylacetate → 1-Piperidineacetic acid, ethyl ester

HRID 432811

反応式

HRID 432811 の反応式
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3](CC(OCC)=O)[CH2:2]1.[CH2:13]([O:15][C:16](=[O:24])[CH2:17]C1C=CC=CN=1)[CH3:14]>>[N:1]1([CH2:17][C:16]([O:15][CH2:13][CH3:14])=[O:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

参加物

3

反応物 2

HCID 75960Ethyl 2-pyridylacetateHCID 2760464Ethyl 2-(piperidin-3-yl)acetate

生成物 1

HCID 6434661-Piperidineacetic acid, ethyl ester

実験手順

The reaction was run in the same manner as ethyl 3-piperidinylacetate, starting with commercially available ethyl-2-pyridylacetate (4.00 g; 24.5 mmol). This gave ethyl 2-piperidinylacetate (2.41 g) as a light yellow oil without further purification. MS m/z (positive ion) 172 (MH+; 100).

後処理

  1. customThis gave ethyl 2-piperidinylacetate (2.41 g) as a light yellow oil without further purification

出典と根拠

ORDレコード
ord-885d55a01d27437bb29c8817847259b2
出典データセット
uspto-grants-2003_12
特許番号
US06664271B1

関連ノート

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