Allyl bromide → 1,3-Butadienylferrocene

HRID 433007

反応式

HRID 433007 の反応式
[C-:1]1(C=O)[CH:5]=[CH:4][CH:3]=[CH:2]1.[CH-]1C=CC=C1.[Fe+2:13].CC([C-]1C=CC=C1)=O.[CH-]1C=CC=C1.[Fe+2].C(Br)C=C.[C-:32]1([CH:37](O)[CH2:38][CH:39]=[CH2:40])[CH:36]=[CH:35][CH:34]=[CH:33]1.[CH-]1C=CC=C1.[Fe+2]>CCOCC.[Mg]>[C-:32]1([CH:37]=[CH:38][CH:39]=[CH2:40])[CH:36]=[CH:35][CH:34]=[CH:33]1.[CH-:1]1[CH:5]=[CH:4][CH:3]=[CH:2]1.[Fe+2:13]

参加物

7

反応物 4

HCID 7841Allyl bromideHCID 15184314FerrocenecarboxyaldehydeHCID 178450094HCID 178450094、化合物HCID 178466060HCID 178466060、化合物

生成物 1

HCID 1296652321,3-Butadienylferrocene

試薬・触媒・溶媒 2

HCID 5462224Magnesium触媒HCID 3283Diethyl Ether溶媒

実験手順

Ferrocenaldehyde or ferrocenyl methyl ketone and allyl bromide are reacted in an ether solvent and in the presence of magnesium metal as a catalyst. The liquid portion of the reaction mixture is introduced into a silica gel column, wherein the weak acidity of the silica gel is able to dehydrate the reaction intermediate 1-ferrocenyl-3-buten-1-ol product. The column is eluted with n-hexane, and after evaporating the solvent from the eluate collected, a purified ferrocenyl-1,3-butadiene product is obtained.

後処理

  1. additionThe liquid portion of the reaction mixture is introduced into a silica gel column, wherein the weak acidity of the silica gel
  2. washThe column is eluted with n-hexane
  3. customafter evaporating the solvent from the eluate collected

出典と根拠

ORDレコード
ord-1873e47b27344b03a5faf5cb04c75af6
出典データセット
uspto-grants-2003_12
特許番号
US06664409B1

関連ノート

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