p-Toluidine → 2-hydroxy-N-(4-methylphenyl)benzamide

HRID 433027

反応式

HRID 433027 の反応式
[C:1]([O:10]C1C=CC=CC=1)(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][CH:19]=1>>[CH3:24][C:21]1[CH:22]=[CH:23][C:18]([NH:17][C:1](=[O:10])[C:2]2[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=2)[OH:4])=[CH:19][CH:20]=1

参加物

3

反応物 2

HCID 7813p-ToluidineHCID 8361Phenyl Salicylate

生成物 1

HCID 4788052-hydroxy-N-(4-methylphenyl)benzamide

実験手順

The 4′-methyl-salicylanilide was prepared by condensing phenyl salicylate with 4-toluidine then purified as described in Example 2a. A ligand mixture was then prepared from 4′-methyl-salicylanilide and binaphthol using the procedure described in Example 5a. 31P NMR (121.77 MHz): several peaks between 117.1-117.8 ppm.

後処理

  1. customthen purified
  2. customA ligand mixture was then prepared from 4′-methyl-salicylanilide and binaphthol using the procedure

出典と根拠

ORDレコード
ord-fc21bdecdfb54a22b3196ecf9c212560
出典データセット
uspto-grants-2003_12
特許番号
US06664427B1

関連ノート

読み込み中…