Dimethylamine → Octanamide

温度

10 °C

135.03 g of Dimethyl Amine solution is charged at room temperature and cooled to 10±2° C., then Octanoyl Chloride obtained in EXAMPLE 4 is charged at 8 to 12° C. over a period of 2 hours, and the reaction mixture is stirred at 10 to 15° C. for 30 minutes and then stirred at room temperature for 1 hour and the upper organic layer is separated from lower aqueous layer and 29.80 g of Sodium Chloride (20% solution) is added to the organic layer. This organic layer is washed and 9.94 g of Sodium Sulphate is added to the organic layer to take up water, and the mixture is filtered to obtain crude Octanamide.

1. stirringstirred at room temperature for 1 hour
2. customthe upper organic layer is separated from lower aqueous layer and 29.80 g of Sodium Chloride (20% solution)
3. additionis added to the organic layer
4. washThis organic layer is washed
5. addition9.94 g of Sodium Sulphate is added to the organic layer
6. filtrationthe mixture is filtered

ORDレコード

ord-4a453be5931640edaf4b3ab0c2ecdb2b

出典データセット

uspto-grants-2013_09

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US08536355B2