Allyl bromide → 4-Allyloxy-2,2,6,6-tetramethylpiperidine hydrobromide

反応式

[CH2:1]([O:4][CH:5]1[CH2:10][C:9]([CH3:12])([CH3:11])[NH:8][C:7]([CH3:14])([CH3:13])[CH2:6]1)[CH:2]=[CH2:3].C([Br:18])C=C>CCOCC>[BrH:18].[CH2:1]([O:4][CH:5]1[CH2:6][C:7]([CH3:14])([CH3:13])[NH:8][C:9]([CH3:12])([CH3:11])[CH2:10]1)[CH:2]=[CH2:3]

参加物

反応条件

温度: 90 °C

実験手順

A mixture of 9.87 parts of 4-allyloxy-2,2,6,6-tetramethylpiperidine and 3.03 parts of allyl bromide was heated at 90° C. for 96 hours. Ether was added to the cooled reaction mixture and the 4-allyloxy-2,2,6,6-tetramethylpiperidine hydrobromide formed during the reaction was filtered off. The ether solvent was removed by distillation under reduced pressure and the residue purified by chromatography to give 4-allyloxy-1-allyl-2,2,6,6-tetramethylpiperidine.