Hydrochloric Acid → (1-Chloro-1-methylethyl)benzene

HRID 434616

反応式

HRID 434616 の反応式
[ClH:1].[CH3:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[CH2:4].N(C(C1C=CC2C(=CC=C(C(C)(N=C=O)C)C=2)C=1)(C)C)=C=O.[O-]C#N.[Na+].N1C=CC=CC=1>C(Cl)Cl.[Cl-].[Zn+2].[Cl-].O>[CH3:4][C:3]([Cl:1])([CH3:2])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

参加物

9

反応物 5

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 7407Alpha-MethylstyreneHCID 517096Sodium CyanateHCID 200293352,6-Bis(2-isocyanatopropan-2-yl)naphthalene

生成物 1

HCID 70281(1-Chloro-1-methylethyl)benzene

試薬・触媒・溶媒 3

HCID 3007855Zincchloride触媒HCID 962Water溶媒HCID 6344Dichloromethane溶媒3 回

反応条件

温度
4 °C

実験手順

α,α-Dimethylbenzylchloride was prepared by passing a stream of dry hydrogen chloride gas through a solution of methylene dichloride (750 ml.) and α-methylstyrene (500 g, 4.2 moles) at 4° C. The reaction and work-up were employed for the paration of 2,6-bis(1-isocyanato-1-methylethyl)naphthalene described in Example 4. The resulting monochloride was dissolved in 750 ml. methylene dichloride and was added to a cooled (4° C.) catalyst solution previously prepared from anhydrous, 90% sodium cyanate (389 g,5.39 moles), pyridine (50 ml., 0.633 mole), zinc chloride (39.15 g,0.28 mole) and 1 ml. H2O in 1075 ml methylene dichloride.

後処理

  1. customat 4° C
  2. customThe reaction

出典と根拠

ORDレコード
ord-2d2c6a269b1b428c9f05c425567213b9
出典データセット
uspto-grants-1983_08
特許番号
US04399074

関連ノート

読み込み中…