化工社化工社 化学情報印刷レポート · 研究参考用
4-(Trifluoromethyl)aniline → Benzamide, 2-chloro-N-(((4-(trifluoromethyl)phenyl)amino)carbonyl)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(Trifluoromethyl)aniline | HCID 9964 | — |
| 反応物 | 2-Chlorobenzoyl isocyanate | HCID 9942311 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | Benzamide, 2-chloro-N-(((4-(trifluoromethyl)phenyl)amino)carbonyl)- | HCID 156359 | — |
反応手順
18.7 g of 2-chlorobenzoylisocyanate were added to 150 ml of a solution of 17.7 g of 4-trifluoromethylaniline in dry acetonitrile. After stirring at room temperature for a few hours, the crystalline precipitate was sucked off, washed with successively acetonitrile, ethanol and petroleum ether and dried in air. The desired product was obtained in a yield of 29.0 g; melting point 214° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04399152 |
| 出典データセット | uspto-grants-1983_08 |
| ORD ID | ord-3da5bf644e3242919dcb62b403d6b719 |
| 出典メモ | uspto-grants-1983_08 |