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HRID434715

反应详情

EQUATION

反应方程式

HRID 434715 的结构方程式

REACTANTS

反应物

2
结构：Nc1ccc(C(F)(F)F)cc1
HCID9964

4-(Trifluoromethyl)aniline

C7H6F3N

结构：O=C=NC(=O)c1ccccc1Cl
HCID9942311

2-CHLOROBENZOYL ISOCYANATE

C8H4ClNO2

PRODUCTS

生成物

1
结构：O=C(NC(=O)c1ccccc1Cl)Nc1ccc(C(F)(F)F)cc1
HCID156359

Benzamide, 2-chloro-N-(((4-(trifluoromethyl)phenyl)amino)carbonyl)-

C15H10ClF3N2O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

18.7 g of 2-chlorobenzoylisocyanate were added to 150 ml of a solution of 17.7 g of 4-trifluoromethylaniline in dry acetonitrile. After stirring at room temperature for a few hours, the crystalline precipitate was sucked off, washed with successively acetonitrile, ethanol and petroleum ether and dried in air. The desired product was obtained in a yield of 29.0 g; melting point 214° C.

WORKUP

后处理

  1. washwashed with successively acetonitrile, ethanol and petroleum ether
  2. customdried in air