N-Iodosuccinimide → ethyl 5-ethyl-4-iodo-1H-imidazole-2-carboxylate

HRID 43505ノート

反応式

HRID 43505 の反応式
[CH2:1]([C:3]1[NH:7][C:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[N:5][CH:4]=1)[CH3:2].C1C(=O)N([I:20])C(=O)C1>>[CH2:1]([C:3]1[NH:7][C:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[N:5][C:4]=1[I:20])[CH3:2]

参加物

3

反応物 2

HCID 120273N-IodosuccinimideHCID 14990237Ethyl 5-ethyl-1H-imidazole-2-carboxylate2 回

生成物 1

HCID 68405791ethyl 5-ethyl-4-iodo-1H-imidazole-2-carboxylate収率 100%

実験手順

The same operation as in Example (1c) was performed using ethyl 5-ethyl-1H-imidazole-2-carboxylate obtained by the method described in Example (1b) (0.20 g, 1.19 mmol) and NIS (0.29 g, 1.31 mmol), to obtain 0.35 g of the title compound as a pale yellow solid (100%).

後処理

  1. customobtained by the method

出典と根拠

ORDレコード
ord-996c4fc53a0f4e24a3049abe2e5d0e9f
出典データセット
uspto-grants-2013_09
特許番号
US08536197B2

反応ノート

読み込み中…