Ammonia → N-trimethylsilyl-4-nitrobenzamide

HRID 435189

反応式

HRID 435189 の反応式
[CH3:1][Si:2]([CH3:9])([CH3:8])[NH:3][Si](C)(C)C.[N+:10]([C:13]1[CH:21]=[CH:20][C:16]([C:17](N)=[O:18])=[CH:15][CH:14]=1)([O-:12])=[O:11].C1C=C2C3=C(C(NC(=O)C3=CC=C2)=O)C=1.N>C(OCCCC)(=O)C>[CH3:1][Si:2]([CH3:9])([CH3:8])[NH:3][C:17](=[O:18])[C:16]1[CH:15]=[CH:14][C:13]([N+:10]([O-:12])=[O:11])=[CH:21][CH:20]=1

参加物

6

反応物 4

HCID 222Ammonia2 回HCID 120914-NitrobenzamideHCID 13838HexamethyldisilazaneHCID 66491Naphthalimide

生成物 1

HCID 12726300N-trimethylsilyl-4-nitrobenzamide

試薬・触媒・溶媒 1

HCID 31272Butyl Acetate溶媒

実験手順

4.5 ml of hexamethyldisilazane (22 mmoles) were added to a refluxing mixture of 5.0 g (30.1 mmoles) of 4-nitrobenzamide, 100 mg (0.5 mmole) of 1.8-naphthalimide and 20 ml of butyl acetate and the calculated amount of ammonia was evolved after refluxing for 35 minutes. The same experiment without catalyst was carried out and only 16% of the theoretical amount of ammonia was evolved after refluxing for 15 minutes. After refluxing for 1 hour, 83% of that amount of evolved.

後処理

  1. temperatureafter refluxing for 35 minutes
  2. temperatureafter refluxing for 15 minutes
  3. temperatureAfter refluxing for 1 hour

出典と根拠

ORDレコード
ord-f9c9ab949fa740f8b6236a8a66d7f676
出典データセット
uspto-grants-1983_08
特許番号
US04400509

関連ノート

読み込み中…