Thionyl Chloride → HCID 15619001、化合物
反応式
[C:1]1([S:7][C:8]2[CH:15]=[CH:14][C:13]([C:16]([F:19])([F:18])[F:17])=[CH:12][C:9]=2[CH2:10]O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:22])=O>C1C=CC=CC=1>[C:1]1([S:7][C:8]2[CH:15]=[CH:14][C:13]([C:16]([F:19])([F:18])[F:17])=[CH:12][C:9]=2[CH2:10][Cl:22])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
4
実験手順
96 g of 2-(phenylthio)-5-trifluoromethyl-benzyl alcohol are dissolved in 450 ml of absolute benzene and heated to reflux. The solution thus obtained is treated dropwise over a period of 20 minutes with 48 ml of thionyl chloride and the mixture is subsequently stirred at reflux for 30 minutes. After cooling, the mixture is evaporated under reduced pressure. There is obtained 2-(phenylthio)-5-trifluoromethyl-benzyl chloride as a brown-yellow oil.
後処理
- temperatureheated to reflux
- customThe solution thus obtained
- temperatureat reflux for 30 minutes
- temperatureAfter cooling
- customthe mixture is evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-3b912a9eb34546278b7e28fe7a7b6651
- 出典データセット
- uspto-grants-1977_02
- 特許番号
- US04006144
反応ノート
読み込み中…