Salicyloyl chloride → HCID 178513857、化合物

HRID 435735

反応式

HRID 435735 の反応式
[Na+].[NH:2]1[CH:6]=[N:5][C:4]([C:7]([NH-:9])=[O:8])=[N:3]1.[C:10](Cl)(=[O:18])[C:11]1[C:12](=[CH:14][CH:15]=[CH:16][CH:17]=1)[OH:13]>C(#N)C>[C:10]([C:6]1[NH:2][N:3]=[C:4]([C:7]([NH2:9])=[O:8])[N:5]=1)(=[O:18])[C:11]1[C:12](=[CH:14][CH:15]=[CH:16][CH:17]=1)[OH:13]

参加物

4

反応物 2

HCID 74041Salicyloyl chlorideHCID 178514233HCID 178514233、化合物

生成物 1

HCID 178513857HCID 178513857、化合物

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

A 25 ml. portion of dry acetonitrile is added to a mixture of 1.3 g. of the s-triazole carboxamide sodium salt and 2 g. of salicyloyl chloride followed by a few pellets of 4A molecular sieves. The mixture is stirred at room temperature for 16 hours and then filtered through Celite. The colorless solid is obtained on evaporating the filtrate is washed with diethyl ether; yield, 1 g., m.p. 147°-150° C. (dec.). Its infrared spectrum is essentially the same as that obtained from the product in Example 7.

後処理

  1. filtrationfiltered through Celite
  2. customThe colorless solid is obtained
  3. customon evaporating the filtrate
  4. washis washed with diethyl ether
  5. customyield
  6. customthat obtained from the product in Example 7

出典と根拠

ORDレコード
ord-fc5a8c5d9c524162bb776eeae08319f4
出典データセット
uspto-grants-1977_02
特許番号
US04006159

関連ノート

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