Benzene → 1-Chloro-5-methoxy-2,6-dimethylheptane

HRID 435781ノート

反応式

HRID 435781 の反応式
O[CH2:2][CH:3]([CH3:12])[CH2:4][CH2:5][CH:6]([O:10][CH3:11])[CH:7]([CH3:9])[CH3:8].S(Cl)([Cl:15])=O.C1C=CC=CC=1>CN(C)C=O>[Cl:15][CH2:2][CH:3]([CH3:12])[CH2:4][CH2:5][CH:6]([O:10][CH3:11])[CH:7]([CH3:9])[CH3:8]

参加物

5

反応物 3

HCID 241BenzeneHCID 24386Thionyl ChlorideHCID 213991185-Methoxy-2,6-dimethylheptan-1-ol

生成物 1

HCID 213990831-Chloro-5-methoxy-2,6-dimethylheptane

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

A mixture of 3.4 g. of 1-hydroxy-5-methoxy-2,6-dimethylheptane and 3 g. of thionyl chloride and 60 ml. of dry benzene is treated with 0.2 ml. of dry dimethylformamide and then refluxed for 6 hours. After cooling, the mixture is decanted and 1-chloro-5-methoxy-2,6-dimethylheptane isolated by filtration through silica gel and distillation.

後処理

  1. additionA mixture of 3.4 g
  2. temperatureAfter cooling
  3. customthe mixture is decanted

出典と根拠

ORDレコード
ord-7a39b80d0e5a4a259274a3e4984dbe18
出典データセット
uspto-grants-1977_02
特許番号
US04006188

反応ノート

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