2-Pentanone → 1-Bromo-trans-1-octen-3-one

HRID 436094

反応式

HRID 436094 の反応式
Cl/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[Br-:11].[Li+].CC(=O)CCC>>[Br:11]/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

参加物

4

反応物 3

HCID 78952-PentanoneHCID 82050Lithium BromideHCID 110410031-Chloro-trans-1-octen-3-one

生成物 1

HCID 117903381-Bromo-trans-1-octen-3-one

実験手順

A mixture of 68.0 g. (0.424 mole) of 1-chloro-trans-1-octen-3 one (Example 723) and 444 g. (4.24 moles) of anhydrous lithium bromide in 900 ml. of 2-pentanone is refluxed for 30 minutes, cooled, and partitioned between ice water and either. The organic phase is washed with water and saturated brine, dried (NaSO4), and evaporated to an oil. This material is used directly without purification.

後処理

  1. additionA mixture of 68.0 g
  2. temperaturecooled
  3. custompartitioned between ice water
  4. washThe organic phase is washed with water and saturated brine
  5. dry with materialdried (NaSO4)
  6. customevaporated to an oil
  7. customThis material is used directly without purification

出典と根拠

ORDレコード
ord-84057573e3f74320bbd6ddedd7ba4a9f
出典データセット
uspto-grants-1977_02
特許番号
US04007210

関連ノート

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