Bromine → Butyl 3-bromo-2-oxopentanoate
反応式
[O:1]=[C:2]([CH2:10][CH2:11][CH3:12])[C:3]([O:5][CH2:6][CH2:7][CH2:8][CH3:9])=[O:4].[Br:13]Br>C(Cl)(Cl)Cl>[Br:13][CH:10]([CH2:11][CH3:12])[C:2](=[O:1])[C:3]([O:5][CH2:6][CH2:7][CH2:8][CH3:9])=[O:4]参加物
4
実験手順
The same operation as in Example (106a) was performed using butyl 2-oxopentanoate (described in Akimova, L. N.; Bel'di, E. S.; J. Org. Chem. USSR (Engl. Transl.); 5; 9; 1969; 1530-1531; Zh. Org. Khim.; 5; 9; 1969; 1569-1571, 13.2 g, 76.7 mmol), bromine (3.59 mL, 70 mmol) and chloroform (80 mL), to obtain 18.5 g of the title compound as a colorless liquid (99%).
出典と根拠
- ORDレコード
- ord-5ebb3b38030541ad992c869ed62ac564
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08536197B2
反応ノート
読み込み中…