Hydrochloric Acid → 1-(2-Pentylidenehydrazino)-3,4-dihydroisoquinoline

HRID 436433

反応式

HRID 436433 の反応式
[CH:1](=O)[CH2:2][CH2:3][CH2:4][CH3:5].[NH:7]([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11][N:10]=1)[NH2:8].Cl>CCOCC>[CH:1](=[N:8][NH:7][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11][N:10]=1)[CH2:2][CH2:3][CH2:4][CH3:5]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 8063PentanalHCID 123490411-Hydrazinyl-3,4-dihydroisoquinoline

生成物 1

HCID 570944031-(2-Pentylidenehydrazino)-3,4-dihydroisoquinoline

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

Valeraldehyde (5.14 g.) was added to a refluxing solution of 1-hydrazino-3,4-dihydroisoquinoline (8 g.) in ether (300 ml.). The mixture was allowed to stand (for 45 min.) at room temperature. Ethereal hydrochloric acid was added. Recrystallization of the resulting solid from ethanol-ether gave 1-(2-pentylidenehydrazino)-3,4-dihydroisoquinoline (I: X=CH3 (CH2)3, X'=Y=Y'=Z=Z'=H) hydrochloride in two crops (11.6 g. and 0.2 g., m.p. 147°-148° C.).

後処理

  1. custom(for 45 min.)
  2. customat room temperature
  3. customRecrystallization of the resulting solid from ethanol-ether

出典と根拠

ORDレコード
ord-044fc138a3be4b3e90b4e14608d19a88
出典データセット
uspto-grants-1977_02
特許番号
US04009170

関連ノート

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