Thionyl Chloride → HCID 21430653、化合物

HRID 437200ノート

反応式

HRID 437200 の反応式
C([O:3][C:4]([C:6]1[O:7][C:8]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH2:18][CH:19](O)[CH2:20][O:21][C:22]3[C:27]4[C:28](=[O:37])[CH:29]=[C:30]([C:32]([O:34]CC)=[O:33])[O:31][C:26]=4[CH:25]=[CH:24][CH:23]=3)[C:9]=2[C:10](=[O:12])[CH:11]=1)=[O:5])C.S(Cl)([Cl:41])=O>ClCCCl>[Cl:41][CH:19]([CH2:20][O:21][C:22]1[C:27]2[C:28](=[O:37])[CH:29]=[C:30]([C:32]([OH:34])=[O:33])[O:31][C:26]=2[CH:25]=[CH:24][CH:23]=1)[CH2:18][O:17][C:13]1[C:9]2[C:10](=[O:12])[CH:11]=[C:6]([C:4]([OH:3])=[O:5])[O:7][C:8]=2[CH:16]=[CH:15][CH:14]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 204318Cromophene

生成物 1

HCID 21430653HCID 21430653、化合物

試薬・触媒・溶媒 1

HCID 111,2-Dichloroethane溶媒

実験手順

A mixture of 24.5 parts of 5,5'-[(2-hydroxytrimethylene)dioxy]bis [4-oxo-4H-1-benzopyran-2-carboxylic acid] diethyl ester and 47.6 parts of thionyl chloride in 40 parts of dry 1,2-dichloroethane was refluxed for 16 hours. The solvent was then evaporated, the residue was triturated with petrol and the resulting solid was crystallized from ethanol to give 15.6 parts of 5,5'-[(2-chlorotrimethylene)dioxy]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid], diethyl ester as white crystals m.p. 144°-144.5° C.

後処理

  1. temperaturewas refluxed for 16 hours
  2. customThe solvent was then evaporated
  3. customthe residue was triturated with petrol
  4. customthe resulting solid was crystallized from ethanol

出典と根拠

ORDレコード
ord-cd0b45c5018846c6a64979c86d933310
出典データセット
uspto-grants-1977_06
特許番号
US04029802

反応ノート

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