Sodium Carbonate → 1,3-Bis[4-(2-formylhydrazino)phenyl]thiourea

HRID 437287

反応式

HRID 437287 の反応式
[C:1](=[O:4])([O-])[O-].[Na+].[Na+].C(CS[C:12](=[S:18])SCC(O)=O)(O)=O.[CH:19]([NH:21][NH:22][C:23]1[CH:28]=[CH:27][C:26]([NH2:29])=[CH:25][CH:24]=1)=[O:20]>O>[CH:19]([NH:21][NH:22][C:23]1[CH:28]=[CH:27][C:26]([NH:29][C:12]([NH:29][C:26]2[CH:27]=[CH:28][C:23]([NH:22][NH:21][CH:1]=[O:4])=[CH:24][CH:25]=2)=[S:18])=[CH:25][CH:24]=1)=[O:20]

参加物

5

反応物 3

HCID 10340Sodium Carbonate2 回HCID 806183,5-Dithia-4-thioxo-1,7-heptanedioic acidHCID 113189Hydrazinecarboxaldehyde, 2-(4-aminophenyl)-

生成物 1

HCID 196096521,3-Bis[4-(2-formylhydrazino)phenyl]thiourea

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
95 °C

実験手順

Sodium carbonate (2.1 g, 0.02 mole) was dissolved in water (100 ml). Bis(carboxymethyl)trithiocarbonate (4.5 g, 0.02 mole) was added portionwise with vigorous stirring. The pH of the reaction mixture was adjusted to 9.5 by the addition of sodium carbonate. The mixture was then heated to approximately 95° C. 1-Formyl-2-(4-aminophenyl)hydrazine (6.5 g, 0.043 mole) was added in one portion to the reaction mixture. Stirring was continued for five minutes. The reaction mixture was chilled, the solid was filtered off, washed thoroughly with water and dried. Yield 4.5 g (66%), m.p. 212°-214° C.

後処理

  1. temperatureThe reaction mixture was chilled
  2. filtrationthe solid was filtered off
  3. washwashed thoroughly with water
  4. customdried

出典と根拠

ORDレコード
ord-d3838d8d3dc54476bb9561df8d3fd504
出典データセット
uspto-grants-1977_06
特許番号
US04030925

関連ノート

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