Triethylamine → 2-[2-(3-Chloro-2-ethylisoindol-1-yl)vinyl]-3-ethylbenzothiazolium perchlorate

HRID 437321

反応式

HRID 437321 の反応式
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[Cl:6][C:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9](=[CH:16]N(C)C)[N+:8]=1[CH2:20][CH3:21].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH2:33]([N+:35]1[C:39]2[CH:40]=[CH:41][CH:42]=[CH:43][C:38]=2[S:37][C:36]=1[CH3:44])[CH3:34].C(N(CC)CC)C>C(#N)C>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[Cl:6][C:7]1[N:8]([CH2:20][CH3:21])[C:9]([CH:16]=[CH:44][C:36]2[S:37][C:38]3[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=3[N+:35]=2[CH2:33][CH3:34])=[C:10]2[C:15]=1[CH:14]=[CH:13][CH:12]=[CH:11]2

参加物

5

反応物 3

HCID 8471TriethylamineHCID 84711Benzothiazolium, 3-ethyl-2-methyl-, 4-methylbenzenesulfonate (1:1)HCID 178462637HCID 178462637、化合物

生成物 1

HCID 867348732-[2-(3-Chloro-2-ethylisoindol-1-yl)vinyl]-3-ethylbenzothiazolium perchlorate

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

3-chloro-1-dimethylaminomethylene-2-ethyl-1H-isoindolium perchlorate (0.5 g) and 3-ethyl-2-methylbenzothiazolium p-toluene sulfonate (0.5 g) were dissolved in acetonitrile and triethylamine added. After 30 minutes at room temperature the product was precipitated by the addition of ether and purified by chromatography on silica gel. After recrystalization from ethanol, the purified product melted at 244° C. CH3CN λ max 553 nm.

後処理

  1. customAfter 30 minutes at room temperature the product was precipitated by the addition of ether
  2. custompurified by chromatography on silica gel
  3. customAfter recrystalization from ethanol

出典と根拠

ORDレコード
ord-13d3865f537c48a4a4becfb064f61741
出典データセット
uspto-grants-1977_06
特許番号
US04030932

関連ノート

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