Hydrochloric Acid → 3-Methoxyphenylhydrazine hydrochloride

HRID 4383

反応式

HRID 4383 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH2:6].[N:10]([O-])=O.[Na+].[Sn].[ClH:15]>O>[ClH:15].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH:6][NH2:10])[CH:7]=[CH:8][CH:9]=1

参加物

6

反応物 4

HCID 313Hydrochloric Acid2 回HCID 108243-MethoxyanilineHCID 5352426Tin atomHCID 23668193Sodium Nitrite

生成物 1

HCID 27239403-Methoxyphenylhydrazine hydrochloride

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A suspension of 3-methoxyaniline (10 g) in concentrated hydrochloric acid (85 ml) was stirred at ca. 0° and a solution of sodium nitrite (5.75 g) in water (25 ml) was slowly added over a period of 30 min keeping the temperature of the mixture at ca. 0°. After 1 h a solution of tin II chloride dihydrate (59 g) in concentrated hydrochloric acid (50 ml) was added over a period of 1.5 h, to the cooled suspension keeping the temperature below 0° C. The suspension was stirred for a further 30 min, filtered and washed with dried ether to give the title compound as a solid (14 g) m.p. 171°.

後処理

  1. customat ca. 0°
  2. customthe temperature below 0° C
  3. stirringThe suspension was stirred for a further 30 min
  4. filtrationfiltered
  5. washwashed with dried ether

出典と根拠

ORDレコード
ord-f29eda88a35249c99e36ce3a1f68295a
出典データセット
uspto-grants-1988_02
特許番号
US04725615

関連ノート

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