Hydrogen Cyanide → Isophorone

HRID 440131

反応式

HRID 440131 の反応式
[O:1]=[C:2]1[CH2:9][C:6]([CH3:8])([CH3:7])[CH2:5][C:4]([CH3:10])=[CH:3]1.COC(=O)[O-].C([N+](C)(C)C)CCC.[CH:24]#[N:25].OP(O)(O)=O>>[O:1]=[C:2]1[CH2:9][C:6]([CH3:8])([CH3:7])[CH2:5][C:4]([CH3:10])=[CH:3]1.[C:24]([C:4]1([CH3:10])[CH2:5][C:6]([CH3:8])([CH3:7])[CH2:9][C:2](=[O:1])[CH2:3]1)#[N:25]

参加物

6

反応物 4

HCID 768Hydrogen CyanideHCID 1004Phosphoric AcidHCID 6544Isophorone2 回HCID 10921347HCID 10921347、化合物

生成物 2

HCID 6544IsophoroneHCID 990683-Cyano-3,5,5-trimethylcyclohexanone

実験手順

To 622 g (4.5 mol) of isophorone in the presence of 4.14 g (0.02mol) of butyltrimethylammonium methylcarbonate there are added 288.3 g of a mixture of 3 mol of HCN and 1.5 mol of isophorone over a period of 120 min and at a temperature of 115° C. Following neutralization with 4 g of H3PO4 the mixture is distilled. There are obtained 424.3 g of isophorone and 478.3 g of 3-cyano-3,5,5-trimethylcyclohexanone. This is equivalent to a yield of 98.8% based on converted isophorone and 96.5% based on HCN used.

後処理

  1. customat a temperature of 115° C
  2. distillationis distilled

出典と根拠

ORDレコード
ord-15a255fe33ea4c8bb3f29466a1da3a33
出典データセット
uspto-grants-1996_05
特許番号
US05516928

関連ノート

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