関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Sodium benzenesulfonate | HCID 517327 | — |
| 反応物 | 2-(Chloromethyl)-1,3-benzoxazole | HCID 2061989 | — |
| 生成物 | 2-(Phenylsulfonyl)-methyl-benzoxazole | HCID 21420294 | — |
反応手順
33 g (0.2 mole) of 2-chloromethylbenzoxazole and 32.8 g of sodium benzene sulfonate were dissolved in 200 ml of DMF, heated within one-half hour to 70° C., for 1 hour at 70° C., for 1 hour to 80° C. and for 1 hour to 90° C., and after cooling, allowed to flow into 300 ml of H2O, while stirring well. The reaction mixture was filtered with suction, washed well with H2O and dried. 48.8 g (98.4 % of the theory) were obtained. After recrystallization from ethanol, 41 g of colorless cristals melting at 108° to 109° C. were obtained. ##STR28##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04039531 |
|---|
| 出典データセット | uspto-grants-1977_08 |
|---|
| ORD ID | ord-0ad286eaae8b46f0800b2c86bbd93a75 |
|---|
| 出典メモ | uspto-grants-1977_08 |
|---|
