Methyl iodide → Hydrazine
反応式
Cl.[CH3:2][CH:3]1[CH2:7][NH:6][C:5]([NH:8][NH2:9])=[N:4]1.CC1CN[C:13](=[S:16])N1.C[I:18]>C(O)C>[IH:18].[CH3:2][CH:3]1[CH2:7][NH:6][C:5]([S:16][CH3:13])=[N:4]1.[NH2:8][NH2:9]参加物
6
実験手順
The starting material, 4-methyl-2-imidazolin-2-ylhydrazine hydrochloride, is prepared as follows: 4-methylimidazolidin-2-thione and methyl iodide react in refluxing ethanol to give 4-methyl-2-methylthio-2-imidazoline hydroiodide, which upon treatment with hydrazine in boiling ethanol yields 4-methyl-2-imidazolin-2-ylhydrazine hydroiodide. Subsequent treatment with silver chloride in aqueous or ethanol solution then gives the hydrochloride salt melting at 128°-130° C.
出典と根拠
- ORDレコード
- ord-aa83b4f6ff5b4025b5a64cfb28aa0e9e
- 出典データセット
- uspto-grants-1977_08
- 特許番号
- USRE029358
反応ノート
読み込み中…