Hydrazinecarboxylic acid, ethyl ester → Ethyl N'-[1-(4-chloro-phenyl)-2-hydroxy-ethylidene]-hydrazinecarboxylate
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH2:9][OH:10])=[CH:4][CH:3]=1.[NH:12]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[NH2:13]>C(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[N:13][NH:12][C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH2:9][OH:10])=[CH:4][CH:3]=1参加物
4
反応条件
- 温度
- 0 °C
実験手順
A mixture of the compound obtained in Step A (195 mmoles) and ethyl hydrazine-carboxylate (224 mmoles) in ethanol is stirred at reflux for 18 hours. The reaction mixture is cooled to 0° C. and the precipitate formed is filtered off, washed with ethyl ether and dried in vacuo to yield the title product, which is used directly in the next Step.
後処理
- temperatureat reflux for 18 hours
- customthe precipitate formed
- filtrationis filtered off
- washwashed with ethyl ether
- customdried in vacuo
出典と根拠
- ORDレコード
- ord-912b3ef24dad40888753f41f5d19cd2f
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08541412B2
反応ノート
読み込み中…