Methanol → 1H-Indole, 3-(methoxymethyl)-

HRID 443316ノート

反応式

HRID 443316 の反応式
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:10][OH:11])=[CH:2]1.[CH3:12]O>O>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:10][O:11][CH3:12])=[CH:2]1

参加物

4

反応物 2

HCID 887Methanol3 回HCID 3712Indole-3-Carbinol

生成物 1

HCID 1544111H-Indole, 3-(methoxymethyl)-

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

Relatively pure 1H-indole-3-methanol (I3C™ from Designed Nutritional Products, Orem, UT, US) in a water solution was prepared for HPLC analysis. One sample was diluted with water and the other was diluted with methanol. By the time the partial methanol solution could be injected into the HPLC, the reaction with methanol had taken place to form 1H-indol-3-yl methoxy methane, the methyl ether of 1H-indole-3-methanol, and two peaks of about the same magnitude were observed. The same solution when diluted with water showed only one peak.

出典と根拠

ORDレコード
ord-9c17ecac43234beeaadb3d6b3e14c901
出典データセット
uspto-grants-1999_04
特許番号
US05895787

反応ノート

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