N,N-Dimethylglycine → HCID 155684、化合物

HRID 443563ノート

反応式

HRID 443563 の反応式
[OH:1][CH2:2][N:3]1[C:7](=[O:8])[C:6]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[NH:5][C:4]1=[O:21].[CH3:22][N:23]([CH3:28])[CH2:24][C:25](O)=[O:26].C1(N=C=NC2CCCCC2)CCCCC1>N1C=CC=CC=1>[CH3:22][N:23]([CH3:28])[CH2:24][C:25]([O:1][CH2:2][N:3]1[C:7](=[O:8])[C:6]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[NH:5][C:4]1=[O:21])=[O:26]

参加物

5

反応物 3

HCID 673N,N-DimethylglycineHCID 10868DicyclohexylcarbodiimideHCID 1613663-(Hydroxymethyl)phenytoin

生成物 1

HCID 155684HCID 155684、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

Into a suitable reaction vessel containing 5 ml of pyridine, there is added one g (0.0035 mols) of 3-hydroxymethyl-diphenylhydantoin, 0.36 g (0.0035 mols) of N,N-dimethylglycine and 0.79 g (0.0035 mols) of dicyclohexylcarbodiimide (DCCI). The reaction mixture is stirred at room temperature for a period of approximately 24 hours, after which the final product, mp 128°-130°, yield 0.86 g (66.7%) is obtained.

出典と根拠

ORDレコード
ord-fb3db23805734015b428dec0cec2bf13
出典データセット
uspto-grants-1981_04
特許番号
US04260769

反応ノート

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