1,3-Dichloroacetone → HCID 86736622、化合物

HRID 444007ノート

反応式

HRID 444007 の反応式
[Cl:1][CH2:2][C:3]([CH2:5]Cl)=O.[CH2:7]([NH:11][C:12]([NH:14][C:15]([NH2:17])=[S:16])=[NH:13])[CH2:8][CH2:9][CH3:10]>CC(C)=O>[ClH:1].[CH2:7]([N:11]=[C:12]([NH2:13])[NH:14][C:15]1[S:16][CH:5]=[C:3]([CH2:2][Cl:1])[N:17]=1)[CH2:8][CH2:9][CH3:10]

参加物

4

反応物 2

HCID 107931,3-DichloroacetoneHCID 178449223HCID 178449223、化合物

生成物 1

HCID 86736622HCID 86736622、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒2 回

実験手順

A solution of 1,3-dichloroacetone (3.02 g.) in acetone (10 ml.) was added to a stirred suspension of (N-n-butylamidino)thiourea (4.04 g.) in acetone (25 ml.) at room temperature. The resulting clear pale yellow solution was stirred for three days, then cooled in ice, and the precipitated solid filtered off and washed with acetone to give 2-(2-n-butylguanidino)-4-chloromethylthiazole hydrochloride.

後処理

  1. temperaturecooled in ice
  2. filtrationthe precipitated solid filtered off
  3. washwashed with acetone

出典と根拠

ORDレコード
ord-84086ea8dd454f728c4a0af36eb519fc
出典データセット
uspto-grants-1981_04
特許番号
US04262126

反応ノート

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