Sodium Hydroxide → Acifluorfen sodium

HRID 444027

反応式

HRID 444027 の反応式
[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([OH:12])=[O:11].[OH-].[Na+:26]>C(O)(C)C>[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:22])([F:23])[F:24])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([O-:12])=[O:11].[Na+:26]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 44073Acifluorfen

生成物 1

HCID 44072Acifluorfen sodium収率 87.9%

試薬・触媒・溶媒 1

HCID 3776Isopropanol溶媒

実験手順

5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (3.0 g, 0.0083 mole) is dissolved in iso-propyl alcohol (20 ml) and a solution of 50% aqueous sodium hydroxide (0.644 g, 0.0083 mole) is added dropwise and the reaction mixture stirred for 1 hour before removing the solvent and water under vacuum at 0.2 mm overnight to afford 2.8 g of sodium 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate.

後処理

  1. custombefore removing the solvent and water under vacuum at 0.2 mm overnight

出典と根拠

ORDレコード
ord-0da14425cea045d3afcb7019d8748db4
出典データセット
uspto-grants-1981_04
特許番号
US04262152

関連ノート

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