Tetrahydrofuran → HCID 13013940、化合物
反応式
[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6][C:5]2[CH:13]=[C:14]([C:17]([OH:19])=[O:18])[CH:15]=[CH:16][C:4]=2[NH:3]1.O1CCC[CH2:21]1>>[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6][C:5]2[CH:13]=[C:14]([C:17]([O:19][CH3:21])=[O:18])[CH:15]=[CH:16][C:4]=2[NH:3]1参加物
3
実験手順
Dissolve 1 gm of the acid of Example 22 with heating in 100 ml of tetrahydrofuran. Filter and cool the filtrate to room temperature. Add 500 mg. of diazomethane and stir at room temperature for 30 minutes. Strip to dryness and triturate the residue in methanol. Recover the title product by filtration. (m.p. 240°-257° C.).
後処理
- filtrationFilter
- additionAdd 500 mg
- customStrip to dryness and triturate the residue in methanol
- customRecover the title product
- filtrationby filtration
出典と根拠
- ORDレコード
- ord-6b27b553b41646a29e28edd664413267
- 出典データセット
- uspto-grants-1981_04
- 特許番号
- US04263207
反応ノート
読み込み中…