2-Tridecanone → 2-Tridecanone oxime

HRID 444249

反応式

HRID 444249 の反応式
[CH2:1]([C:12]([CH3:14])=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[OH:15][NH:16]Cl.[OH-].[Na+]>C(O)C.O>[CH3:14][C:12](=[N:16][OH:15])[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

参加物

6

反応物 3

HCID 116222-TridecanoneHCID 14798Sodium HydroxideHCID 149953Hydroxylamine, N-chloro-

生成物 1

HCID 740543132-Tridecanone oxime収率 93%

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

A solution of 40 g of methyl undecyl ketone and 18 g of hydroxylamino hydrochloride in 200 ml of ethanol, 60 ml of water and 10 g of NaOH is refluxed for 5 hours and thereafter cooled. The ethanol is distilled off in vacuo and the reaction mixture is then diluted with water, extracted with ether and the ethereal extract is dried over Na2SO4. The ether is distilled off and the solid residue is then distilled in vacuo, affording 40 g of 2-tridecanone oxime. Melting point (after recrystallisation from ether); 51°-53° C.

後処理

  1. temperaturecooled
  2. distillationThe ethanol is distilled off in vacuo
  3. additionthe reaction mixture is then diluted with water
  4. extractionextracted with ether
  5. extractionthe ethereal extract
  6. dry with materialis dried over Na2SO4
  7. distillationThe ether is distilled off
  8. distillationthe solid residue is then distilled in vacuo

出典と根拠

ORDレコード
ord-4a76a7bc498041f6abcd50afd442ad9a
出典データセット
uspto-grants-1981_04
特許番号
US04263324

関連ノート

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