Ammonium Chloride → 4-([3-(tert-butyldimethylsilanyloxy)phenyl]{3-[N-(3-fluorophenyl)-N-methyl-carbamoyl]phenyl}hydroxymethyl)piperidine-1-carboxylic acid tert-butyl ester

反応式

C([Li])CCC.[F:6][C:7]1[CH:8]=[C:9]([N:13]([CH3:23])[C:14](=[O:22])[C:15]2[CH:20]=[CH:19][CH:18]=[C:17](I)[CH:16]=2)[CH:10]=[CH:11][CH:12]=1.[C:24]([O:28][C:29]([N:31]1[CH2:36][CH2:35][CH:34]([C:37](=[O:52])[C:38]2[CH:43]=[CH:42][CH:41]=[C:40]([O:44][Si:45]([C:48]([CH3:51])([CH3:50])[CH3:49])([CH3:47])[CH3:46])[CH:39]=2)[CH2:33][CH2:32]1)=[O:30])([CH3:27])([CH3:26])[CH3:25].[NH4+].[Cl-]>C1COCC1.O>[C:24]([O:28][C:29]([N:31]1[CH2:32][CH2:33][CH:34]([C:37]([C:38]2[CH:43]=[CH:42][CH:41]=[C:40]([O:44][Si:45]([C:48]([CH3:51])([CH3:50])[CH3:49])([CH3:46])[CH3:47])[CH:39]=2)([C:17]2[CH:18]=[CH:19][CH:20]=[C:15]([C:14](=[O:22])[N:13]([C:9]3[CH:10]=[CH:11][CH:12]=[C:7]([F:6])[CH:8]=3)[CH3:23])[CH:16]=2)[OH:52])[CH2:35][CH2:36]1)=[O:30])([CH3:27])([CH3:26])[CH3:25]