Triethylamine → 1246210-02-5
反応式
[F:1][C:2]1([F:11])[CH2:7][CH2:6][CH:5](C(O)=O)[CH2:4][CH2:3]1.C1C=CC(OP([O:24][C:25]2C=CC=CC=2)(N=[N+]=[N-])=O)=CC=1.C([N:33](CC)CC)C>C1(C)C=CC=CC=1>[F:11][C:2]1([F:1])[CH2:3][CH2:4][CH:5]([N:33]=[C:25]=[O:24])[CH2:6][CH2:7]1参加物
5
実験手順
A mixture of 4,4-difluorocyclohexanecarboxylic acid (0.20 g, 1.2 mmol) (Matrix Scientific, Cat. #018320), diphenylphosphonic azide (0.67 g, 2.4 mmol) (Aldrich, Cat. #178756) and triethylamine (0.51 mL, 3.6 mmol) in toluene (10 mL) was refluxed overnight. The volatiles were removed under reduced pressure to afford the product which was directly used for next step reaction without further purification.
後処理
- temperaturewas refluxed overnight
- customThe volatiles were removed under reduced pressure
- customto afford the product which
- customwas directly used for next step reaction without further purification
出典と根拠
- ORDレコード
- ord-2cc29ac6cfff4aecab4930936f6dced6
- 出典データセット
- uspto-grants-2013_07
- 特許番号
- US08481732B2
反応ノート
読み込み中…