反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:9]=[CH:10]/[C:11]([O:13][CH3:14])=[O:12])[CH:6]=[N:7][CH:8]=1>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][CH2:10][C:11]([O:13][CH3:14])=[O:12])[CH:6]=[N:7][CH:8]=1参加物
4
実験手順
In Parr apparatus, a mixture of 1 g (5.33 mmol) of methyl (2E)-3-(5-methoxypyridin-3-yl)prop-2-enoate in 20 mL of MeOH and 0.1 g of 10% Pd/C is hydrogenated at 7 bar for 5 hours. The reaction mixture is then filtered through Whatman GF/F paper and concentrated under reduced pressure. 1 g of methyl 3-(5-methoxypyridin-3-yl)propanoate is thus obtained in the form of a wax, which is used without further purification in the following step.
後処理
- filtrationThe reaction mixture is then filtered through Whatman GF/F paper
- concentrationconcentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-6ce0145da8c3440ca591256bc20caa1e
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08541455B2
関連ノート
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