Thionyl Chloride → 3-Nitro-5-(trifluoromethyl)benzoyl chloride
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:12]=1)[C:7](O)=[O:8])([O-:3])=[O:2].S(Cl)([Cl:19])=O>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:12]=1)[C:7]([Cl:19])=[O:8])([O-:3])=[O:2]参加物
3
実験手順
A solution of 3-nitro-5-(trifluoromethyl)benzoic acid (2.00 g, 8.51 mmol) in thionyl chloride (12.4 ml, 170 mmol) was heated at 90° C. for 2 hours. The solution was cooled to room temperature, concentrated, and azeotroped with toluene to provide 3-nitro-5-(trifluoromethyl)benzoyl chloride as a liquid.
後処理
- concentrationconcentrated
- customazeotroped with toluene
出典と根拠
- ORDレコード
- ord-b4a247cdd43344568779fb562d08b5ea
- 出典データセット
- uspto-grants-2013_07
- 特許番号
- US08492371B2
反応ノート
読み込み中…