Sodium Hydroxide → HCID 58508470、化合物

HRID 454773ノート

反応式

HRID 454773 の反応式
[OH-].[Na+:2].[OH:3][C:4]1[CH:5]=[C:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[C:12]([NH:19][C:20]([C:22]3[CH:23]=[N:24][CH:25]=[C:26]([C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=4)[CH:27]=3)=[O:21])[CH:11]=2)[CH:7]=[CH:8][CH:9]=1>C(O)C>[OH:3][C:4]1[CH:5]=[C:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([O-:16])=[O:15])=[C:12]([NH:19][C:20]([C:22]3[CH:23]=[N:24][CH:25]=[C:26]([C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=4)[CH:27]=3)=[O:21])[CH:11]=2)[CH:7]=[CH:8][CH:9]=1.[Na+:2]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 58508471HCID 58508471、化合物

生成物 1

HCID 58508470HCID 58508470、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Ethanol (4.0 mL) and a 1 mol/L aqueous solution of sodium hydroxide (0.17 mL) were sequentially added to the obtained 4-(3-hydroxyphenyl)-2-(5-phenylpyridine-3-carboxamido)benzoic acid (70 mg), followed by stirring at room temperature for 1 hour. The solvent was evaporated under reduced pressure, and ethanol and water were added to the obtained residue. The solid substance was collected by filtration to obtain 26 mg of sodium 4-(3-hydroxyphenyl)-2-(5-phenylpyridine-3-carboxamido)benzoate as a white solid.

後処理

  1. customThe solvent was evaporated under reduced pressure, and ethanol and water
  2. additionwere added to the obtained residue
  3. filtrationThe solid substance was collected by filtration

出典と根拠

ORDレコード
ord-32d6ad06ef954c4fa475b9c67cc8f555
出典データセット
uspto-grants-2013_07
特許番号
US08492582B2

反応ノート

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