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HRID 456241作成日：2026年10月26日

2-Bromo-5-(trifluoromethyl)benzaldehyde → (6-Fluoro-2'-formyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

https://huagongshe.com/reaction/456241

反応式

関与物質

役割名称HCID仕込み量
反応物2-Bromo-5-(trifluoromethyl)benzaldehydeHCID 7018047—
反応物Methyl 2-(4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetateHCID 46739456—
生成物(6-Fluoro-2'-formyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 86633169—

反応手順

Prepared according to the procedure described in Example 25, Step 3, using the following starting materials: 2-bromo-5-trifluoromethyl-benzaldehyde and [4-fluoro-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid methyl ester; the isolated product was further purified by preparative HPLC.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08497381B2
出典データセットuspto-grants-2013_07
ORD IDord-914b9f35f9da455596557ffce904cd50
出典メモuspto-grants-2013_07