Hydrazine hydrate (1:1) → HCID 178477869、化合物
反応式
Cl[C:2]1[C:7]([C:8]([C:10]2[CH:14]=[CH:13][NH:12][CH:11]=2)=O)=[CH:6][CH:5]=[C:4]([Cl:15])[N:3]=1.O.[NH2:17][NH2:18]>C(O)C>[Cl:15][C:4]1[N:3]=[C:2]2[NH:17][N:18]=[C:8]([C:10]3[CH:14]=[CH:13][NH:12][CH:11]=3)[C:7]2=[CH:6][CH:5]=1参加物
4
反応条件
- 温度
- 90 °C
実験手順
A mixture of (2,6-dichloro-pyridin-3-yl)-(1H-pyrrol-3-yl)-methanone (300 mg) and hydrazine hydrate (0.2 mL) in ethanol (10 mL) was heated at 90° C. for 20 hours. The reaction was concentrated to 6 mL, diluted with water (2 mL) and cooled. The precipitate was collected and dried to give 160 mg of the titled compound.
後処理
- concentrationThe reaction was concentrated to 6 mL
- additiondiluted with water (2 mL)
- temperaturecooled
- customThe precipitate was collected
- customdried
出典と根拠
- ORDレコード
- ord-e8c5a7615b094a128dc5606ce408285f
- 出典データセット
- uspto-grants-2007_03
- 特許番号
- US07186716B2
反応ノート
読み込み中…