Methyl iodide → Methyl thiophene-2-carbimidothioate

HRID 458959

反応式

HRID 458959 の反応式
[CH3:1]I.[S:3]1[CH:7]=[CH:6][CH:5]=[C:4]1[C:8](=[S:10])[NH2:9]>CC(C)=O>[S:3]1[CH:7]=[CH:6][CH:5]=[C:4]1[C:8]([S:10][CH3:1])=[NH:9]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 7372372-Thiophenecarbothioamide

生成物 1

HCID 10487134Methyl thiophene-2-carbimidothioate収率 97%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

反応条件

温度
23 °C

実験手順

Methyl iodide (66 g; 0.46 mol) is added drop wise at 0° C. to a solution of thiophene-2-carbothioamide (50 g; 0.33 mol) in 500 ml of acetone. After the addition, stirring is maintained for two hours at 23° C. The precipitate formed is filtered on frit and washed twice with 100 ml of acetone before being dried under vacuum (in a bell jar). A yellow powder is obtained with a yield of 97%.

後処理

  1. additionAfter the addition
  2. customThe precipitate formed
  3. filtrationis filtered on frit
  4. washwashed twice with 100 ml of acetone
  5. custombefore being dried under vacuum (in a bell jar)
  6. customA yellow powder is obtained with a yield of 97%

出典と根拠

ORDレコード
ord-8f32cc83c4a74b9aba1e5ee8bc33045c
出典データセット
uspto-grants-2007_03
特許番号
US07192975B2

関連ノート

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