Aniline → 3-(4-methoxyphenyl)-4-phenyl-5-methyl-4H-1,2,4-triazole

HRID 4596

反応式

HRID 4596 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[P].[CH3:9][O:10][C:11]1[CH:23]=[CH:22][C:14]([C:15]([NH:17][NH:18][C:19](=O)[CH3:20])=O)=[CH:13][CH:12]=1>ClC1C=CC=CC=1Cl>[CH3:9][O:10][C:11]1[CH:23]=[CH:22][C:14]([C:15]2[N:1]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:19]([CH3:20])=[N:18][N:17]=2)=[CH:13][CH:12]=1

参加物

5

反応物 3

HCID 6115AnilineHCID 839858N'-acetyl-4-methoxybenzohydrazideHCID 5462309Phosphorus

生成物 1

HCID 130540233-(4-methoxyphenyl)-4-phenyl-5-methyl-4H-1,2,4-triazole

試薬・触媒・溶媒 1

HCID 72391,2-Dichlorobenzene溶媒

実験手順

Using the procedure of Step B in Example 1, 26.3 ml of aniline, 150 ml of o-dichlorobenzene, 4.65 ml of phosphorus trichlorode and 10 g of N-(4-methoxybenzoyl)-N'-acetyl-hydrazine [prepared by process of J. Org., Vol. 19 (1954), p. 194-201] were reacted to obtain 7.1 g of 3-(4-methoxyphenyl)-4-phenyl-5-methyl -4H-1,2,4-triazole melting at 140°-141° C.

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-afd7c470aaa9450c98ccacd72a59e875
出典データセット
uspto-grants-1988_02
特許番号
US04727084

関連ノート

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