Ethanol → 4-dimethylamino-N'-(4-nitrophenyl)-benzenecarbohydrazonamide

HRID 4600ノート

反応式

HRID 4600 の反応式
[CH3:1][N:2]([CH3:21])[C:3]1[CH:8]=[CH:7][C:6]([C:9](=S)[NH:10]C2C=CC([N+]([O-])=O)=CC=2)=[CH:5][CH:4]=1.[CH2:22](O)[CH3:23].[OH2:25].[NH2:26][NH2:27].[OH2:28]>>[CH3:1][N:2]([CH3:21])[C:3]1[CH:4]=[CH:5][C:6]([C:9](=[N:26][NH:27][C:23]2[CH:22]=[CH:8][C:3]([N+:2]([O-:28])=[O:25])=[CH:4][CH:5]=2)[NH2:10])=[CH:7][CH:8]=1

参加物

5

反応物 4

HCID 702EthanolHCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 131748644-dimethylamino-N-(4-nitrophenyl)-benzenecarbothiamide

生成物 1

HCID 540281914-dimethylamino-N'-(4-nitrophenyl)-benzenecarbohydrazonamide

反応条件

温度
10 °C

実験手順

A suspension of 30 g of the product of Step A and 180 ml of ethanol was heated to reflux and 30 ml of hydrazine hydrate were added thereto. The mixture was refluxed for 15 minutes and then 180 ml of distilled water were added thereto. The mixture was cooled to 10° C. and was vacuum filtered. The product was washed with water and dried to obtain 19 g of 4-dimethylamino-N'-(4-nitrophenyl)-benzenecarbohydrazonamide melting at 174° C.

後処理

  1. temperaturewas heated
  2. temperatureto reflux
  3. temperatureThe mixture was refluxed for 15 minutes
  4. filtrationfiltered
  5. washThe product was washed with water
  6. customdried

出典と根拠

ORDレコード
ord-05f2c0b8eede4b9b9b7b2b83900de675
出典データセット
uspto-grants-1988_02
特許番号
US04727084

反応ノート

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